Table 3.
Factors Associated with Bleeding Requiring Transfusion after Liver Biopsy
| Variable |
No transfusion |
Transfusion | P- value |
|---|---|---|---|
| Overall | 90 (74%) | 31 (26%) | |
| Age at enrollment | 0.81 | ||
| <3 years | 76 (84%) | 25 (81%) | |
| 3-8 years | 10 (11%) | 5 (16%) | |
| >8 years | 4 (4%) | 1 (3%) | |
| 0.22 | |||
| PRETEXTa | |||
| II | 25 (28%) | 11 (35%) | |
| III | 43 (48%) | 17 (55%) | |
| IV | 22 (24%) | 3 (10%) | |
| IV | 22 (24%) | 3 (10%) | |
| 0.96 | |||
| Venous involvement | |||
| V(neg) | 6 (7%) | 2 (6%) | |
| V0 | 6 (7%) | 3 (10%) | |
| V1 | 14 (16%) | 4 (13%) | |
| V2 | 62 (69%) | 21 (68%) | |
| V3 | 2 (2%) | 1 (3%) | |
| 0.77 | |||
| Portal involvement | |||
| P(neg) | 6 (7%) | 1 (3%) | |
| P0 | 7 (8%) | 3 (10%) | |
| P1 | 12 (13%) | 6 (19%) | |
| P2 | 57 (63%) | 20 (65%) | |
| P3 | 8 (9%) | 1 (3%) | |
| Biopsy type | |||
| <0.01 | |||
| Laparoscopic | 13 (14%) | 4 (13%) | |
| Open | 49 (54%) | 27 (87%) | |
| Percutaneous | 28 (31%) | 0 (0%) | |
| Days from biopsy to treatment | 4 (1 - 19) | 5 (1 - 12) | 0.16 |
Number (%) or median (range)
a
Determined by central review
PRETEXT, pretreatment extent of disease