Table 3.
Serum lead and current wheeze in study participants1
| Serum lead (μg/L) |
|
|---|---|
| Exposure | Odds ratio (95% confidence interval) |
| All participants (n = 13,888) | |
| Quartile 1 (<0.83 μg/L) | 1.00 |
| Quartile 2 (0.83 – 1.27 μg/L) | 0.98 (0.81, 1.19) |
| Quartile 3 (1.27 – 2.00 μg/L) | 0.96 (0.78, 1.18) |
| Quartile 4 (≥2.00 μg/L) | 1.15 (0.91, 1.45) P for linear trend = 0.34 |
| Never/former smokers (n = 10,742) | |
| Quartile 1 (<0.78 μg/L) | 1.0 |
| Quartile 2 (0.78 – 1.20 μg/L) | 1.00 (0.81, 1.24) |
| Quartile 3 (1.20 – 1.83 μg/L) | 0.95 (0.76, 1.19) |
| Quartile 4 (≥1.83 μg/L) | 1.10 (0.82, 1.46) P for linear trend = 0.63 |
| Current smokers (n = 3,146) | |
| Quartile 1 (1.04 μg/L) | 1.0 |
| Quartile 2 (1.04 – 1.60 μg/L) | 0.94 (0.67, 1.31) |
| Quartile 3 (1.60 – 2.48 μg/L) | 0.91 (0.59, 1.41) |
| Quartile 4 (≥ 2.48 μg/L) | 1.24 (0.78, 1.96) P for linear trend = 0.43 |
1
All models were adjusted for age, gender, race/ethnicity, annual household income, BMI, family history of asthma, serum cotinine, and occupational exposure to mineral dust or exhaust fumes. The model for all participants was additionally adjusted for smoking status.
2
* P< 0.05 and ** P< 0.01