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. 2019 Nov 6;12:9291–9302. doi: 10.2147/OTT.S229514

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© 2019 Zhai et al.

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Correlation of miR-640 with hsa-circ-0046600 and the expression of miR-640 in HCC. (A) Relative luciferase activity was reduced after the co-transfection of hsa-circ-0046600-WT and miR-640 mimics. The predicted binding sites, sequences and models of hsa-circ-0046600-Mut are shown. (B) siCircRNA0046600 transfection caused a corresponding change in miR-640 in HepG2 cells. (C) The meta-analysis of miR-640 and HCC gene microarrays in the GEO database is shown. (D) miR-640 is negatively correlated with hsa-circ-0046600 in HCC. Data are reported as the mean ± SD. **P-value < 0.01, ***P-value < 0.001.