Table 3.

Changes In FA Values Induced By rTMS

	n	Pre		Post		t	p
Mean	SD	Mean	SD
FA in the left middle frontal gyrus	12	0.588	0.094	0.581	0.080	−0.563	0.585
In the right middle frontal gyrus	12	0.558	0.081	0.588	0.061	1.427	0.181
In the left superior frontal gyrus	12	0.616	0.062	0.606	0.055	−0.871	0.403
In the right superior frontal gyrus	12	0.562	0.070	0.587	0.072	3.512	0.005
Responders
	n	Pre		Post		t	p
Mean	SD	Mean	SD
FA in the left middle frontal gyrus	4	0.532	0.090	0.546	0.073	0.486	0.660
In the right middle frontal gyrus	4	0.551	0.084	0.576	0.064	0.439	0.690
In the left superior frontal gyrus	4	0.608	0.086	0.587	0.069	−1.478	0.236
In the right superior frontal gyrus	4	0.513	0.100	0.533	0.094	1.035	0.377
Non-responders
	n	Pre		Post		t	p
Mean	SD	Mean	SD
FA in the left middle frontal gyrus	8	0.616	0.089	0.599	0.081	−1.449	0.191
In the right middle frontal gyrus	8	0.562	0.085	0.594	0.063	1.829	0.110
In the left superior frontal gyrus	8	0.620	0.052	0.615	0.049	−0.297	0.775
In the right superior frontal gyrus	8	0.587	0.037	0.615	0.042	4.328	0.003

Notes: The region of interest (ROI) approach (n = 12) revealed that white matter fractional anisotropy (FA) in the right superior frontal gyri was significantly increased by rTMS (p = 0.004). In rTMS-responders (n = 4), the ROI approach did not reveal significantly increased white matter FA in any region by rTMS. In rTMS-non-responders (n = 8), the ROI approach revealed that rTMS significantly increased white matter FA in the right superior frontal gyrus.

Abbreviation: FA, fractional anisotropy.