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. 2019 Nov 6;15:3079–3087. doi: 10.2147/NDT.S228501

Table 4.

Correlation Between Changes In FA Values And Frontal Lobe Function As Well As Changes In FA Values And Depressive Symptoms (N=12)

HAM-D BDI WCST WFT CST
CA TE PEN DMS Phoneme Category Part1 Part2 Part3
FA in the left middle frontal gyrus Pearson’s correlation −0.451 −0.204 0.030 0.391 0.471 0.012 −0.757 −0.290 −0.658 −0.715 −0.668
p 0.141 0.524 0.926 0.209 0.123 0.971 0.004 0.360 0.020 0.009 0.018
FA in the right middle frontal gyrus Pearson’s correlation 0.154 0.151 0.191 0.081 0.115 −0.328 −0.698 −0.154 −0.629 −0.516 −0.679
p 0.633 0.639 0.552 0.803 0.722 0.298 0.012 0.632 0.028 0.086 0.015
FA in the left superior frontal gyrus Pearson’s correlation −0.005 0.183 −0.021 0.226 0.405 0.067 0.000 −0.320 0.167 −0.039 0.182
p 0.988 0.570 0.949 0.481 0.192 0.837 0.999 0.310 0.605 0.905 0.571
FA in the right superior frontal gyrus Pearson’s correlation −0.265 −0.201 0.533 0.025 0.126 −0.548 −0.138 −0.146 −0.403 −0.538 −0.232
p 0.405 0.532 0.074 0.939 0.697 0.065 0.670 0.652 0.194 0.071 0.468

Notes: In the region of interest (ROI) analysis, none of the fractional anisotropy (FA) increases in any region were correlated with increases in HAM-D scores, BDI scores, or the improvement of any frontal lobe function (n = 12). The amount of changes in FA values and frontal lobe function was calculated by post-pre comparisons.

Abbreviations: HAMD, Hamilton Depressive Rating Scale; BDI, Beck Depression Inventory; WCST, Wisconsin Card Sorting Test; CA, categories achieved; TE, total errors; PEN, the Perseverative Errors of Nelson; DMS, Difficulties of Maintaining Set; WFT, Word Fluency Test; CST, Color Stroop Test; FA, fractional anisotropy.