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. 2019 Jul 15;68(4):519–529. doi: 10.1538/expanim.19-0018

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©2019 Japanese Association for Laboratory Animal Science

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)

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Fig. 3. — Hair loss and accelerated keratinization in hairless (HR)^−/− piglets. (A) Eyelid skin (boxed area) of HR^−/− and WT piglets at postnatal (PN) day 2. (B) Morphological changes in the back skin of HR^−/− piglets. Transmission electron microscopy analysis of the back skin of HR^−/− and WT piglets at the indicated PN day. The circles denote loss of hairs from the follicles. The arrows indicate keratinized stratified squamous epithelium and detachment of the inner root sheath from the hair shaft.