Fig. 3.

Astragaloside IV (AST-IV) protected mice heart from coxsackievirus B3 (CVB3)-induced cardiac damage and fibrosis. (A) H&E staining of heart sections and quantitative data (scale bars:100 µM, n=6 per group). (B) Picrosirius red-stained transverse sections of the left ventricle from the indicated groups and quantitative data (Scale bars:200 µM, n=6 per group. Upper: image under bright field, lower: image under Polarized light). The data were calculated with GraphPad Prism and presented as mean ± SEM, *P<0.05, **P<0.01 and ***P<0.001.