Table 2. Hematological data in NOG and NSG mice.
Age (weeks) |
Strain (No. of mice) |
RBC (×104/µl) |
HCT (%) |
MCV (fl) |
MCH (pg) |
MCHC (g/dl) |
PLT (×104/µl) |
WBC (×102/µl) |
LYMP (×102/µl) |
EOS (×102/µl) |
||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Male | 9 | NOG (10) | Mean | 849 | 45.1 | 53.1 | 15.6 | 29.4 | 139.3 | 14.5 | 1.8 | 0.5 |
SD | 20 | 1.0 | 0.9 | 0.2 | 0.4 | 8.9 | 4.0 | 0.4 | 0.3 | |||
NSG (10) | Mean | 841 | 44.5 | 52.9 | 15.7 | 29.7 | 131.0 | 11.6 | 1.4 | 0.3** | ||
SD | 25 | 1.3 | 0.8 | 0.2 | 0.3 | 12.0 | 1.9 | 0.5 | 0.1 | |||
11 | NOG (12) | Mean | 859 | 44.2 | 51.5 | 15.4 | 29.9 | 139.8 | 12.9 | 1.8 | 0.5 | |
SD | 16 | 0.9 | 0.5 | 0.2 | 0.3 | 12.9 | 2.5 | 0.4 | 0.2 | |||
NSG (12) | Mean | 842 | 44.0 | 52.3* | 15.7* | 30.0 | 128.2* | 14.0 | 1.7 | 0.3* | ||
SD | 33 | 1.4 | 1.0 | 0.2 | 0.5 | 8.2 | 3.6 | 0.5 | 0.2 | |||
Female | 9 | NOG (5) | Mean | 867 | 44.7 | 51.6 | 15.6 | 30.2 | 117.2 | 13.5 | 1.8 | 0.6 |
SD | 11 | 0.4 | 0.6 | 0.3 | 0.5 | 18.4 | 3.8 | 0.3 | 0.1 | |||
NSG (5) | Mean | 840** | 43.7** | 52.0 | 15.8 | 30.3 | 113.1 | 11.8 | 1.1** | 0.3** | ||
SD | 7 | 0.5 | 0.6 | 0.2 | 0.4 | 8.5 | 1.6 | 0.2 | 0.1 | |||
11 | NOG (6) | Mean | 862 | 44.9 | 52.1 | 15.8 | 30.2 | 120.4 | 15.2 | 1.8 | 0.8 | |
SD | 19 | 1.5 | 0.8 | 0.2 | 0.3 | 20.0 | 11.0 | 0.6 | 0.6 | |||
NSG (6) | Mean | 833 | 43.0* | 51.6 | 15.8 | 30.7* | 107.9 | 11.0 | 1.3 | 0.2 | ||
SD | 28 | 1.2 | 0.8 | 0.3 | 0.3 | 14.6 | 3.4 | 0.3 | 0.1 |
RBC: red blood cell, HCT: hematocrit, MCV: mean corpuscular volume, MCH: mean corpuscular hemoglobin, MCHC: mean corpuscular hemoglobin concentration, PLT: platelet, WBC: white blood cell, LYMP: lymphocyte, EOS: eosinophil. * and **: Significantly different from NOG mice at P<0.05 and P<0.01by Student’s t-test, respectively.