Table 5. Macroscopic findings in NOG and NSG mice.
Tissue | Observation | Sex Age (weeks) |
Male | Female | ||||||
---|---|---|---|---|---|---|---|---|---|---|
9 | 11 | 9 | 11 | |||||||
Strain No. of mice |
NOG | NSG | NOG | NSG | NOG | NSG | NOG | NSG | ||
10 | 10 | 12 | 12 | 10 | 10 | 12 | 12 | |||
Thymus | Rudimentary | 10 | 10 | 12 | 12 | 10 | 10 | 12 | 12 | |
Spleen | Focus, white | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |
Lymph node, submandibular | Rudimentary | 10 | 10 | 12 | 12 | 10 | 10 | 12 | 12 | |
Lymph node, mesenteric | Rudimentary | 10 | 10 | 12 | 12 | 10 | 10 | 12 | 12 | |
Peyer’s patch | Unobservable | 10 | 10 | 12 | 12 | 10 | 10 | 12 | 12 | |
Intestine, jejunum | Diverticulum | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | |
Liver | Focus, white | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | |
Testis | Small | 1 | 0 | 0 | 1 | – | – | – | – | |
Epididymis | Small | 1 | 0 | 0 | 0 | – | – | – | – |