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| Group | Inoculated cell | Cell dose (cells/head) |
Number of mice with tumors (% formation)* | |
|---|---|---|---|---|
| NOG | NSG | |||
| 1 | HeLa | 1 × 103 | 0/8 (0%) | 0/8 (0%) |
| 2 | HeLa | 1 × 104 | 0/8 (0%) | 1/8 (13%) |
| 3 | HeLa | 1 × 105 | 8/8 (100%) | 8/8 (100%) |
| 4 | HeLa | 1 × 106 | 8/8 (100%) | 8/8 (100%) |
| 5 | MRC-5 | 1 × 106 | 0/8 (0%) | 0/7 (0%) |
*: Tumor formation rate was evaluated 16 weeks after inoculation by 1×103, 104, 105 and 106 HeLa cells, and 1×106 MRC-5 cells.
