Figure 9.

Ischemic stroke suppresses the production of multiple cytokines in the lung. A‐L, Lung tissues were homogenized 24 and 72 hours following tMCAO (filled circle) or sham operation (open circle), level of IL‐1β (A), TNF‐α (B), IFN‐γ (C), IL‐17A (D), IL‐27 (E), IL‐1α (F), IL‐6 (G), IL‐12p70 (H), IL‐23 (I), IL‐10 (J), IFN‐β (K), GM‐CSF (L) in the lungs of individual animals was determined by multiplex bead array. Data shown are combined results from three to four independent experiments with n = 12 to 15 animals per group (sham 24 hours, tMCAO 24 hours, sham 72 hours, tMCAO 72 hours). *P < .05; **P < .01. GM‐CSF, granulocyte‐macrophage colony‐stimulating factor; IFN, interferon; IL, interleukin; NS, not statistically different.different; tMCAO, transient middle cerebral artery occlusion; TNF‐α, tumour necrosis factor α