Fig. 2.
Effects of T1D and ER genotype on blood glucose concentration and body weight. A: time course of blood glucose levels in each group of mice. B: change in body weight over the 6-wk period after the injection of streptozotocin (STZ) or vehicle. For both panels, P values for main effects determined by repeated-measures ANOVA are PGroup < 0.001, PTime < 0.001, and PG × T < 0.001. *P < 0.05 vs. Control (of same genotype); †P < 0.05 vs. WT-STZ; §P < 0.05 vs. ERα66KO-STZ. Total number of animals included in each group are shown (n values), not accounting for occasional missing data points over the 6-wk of study.