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Renal expression of β-catenin and sirtuin (SIRT)1 in aged male mice with targeted disruption of the heme oxygenase (HO)-2 gene (HO-2−/− mice) and littermate control (HO-2+/+) mice 6 h after acute renal ischemia (IR). Renal expression of β-catenin and SIRT1 protein was determined by Western blot analysis. Values are means ± SE; n = 4 mice subjected to sham surgery and n = 7 HO-2+/+ and 8 HO-2−/− mice subjected to IR. *P < 0.05 vs. HO-2+/+ mice subjected to IR.
