Some alveolar epithelial cells express markers of both type II cells and type I cells in acute lung injury. Lungs from a normal organ donor and a donor with acute lung injury are shown. A through D are from a donor with normal appearing lung: A: combined image. B: tomato lectin, red. C: HTII-280, green. D: DAPI, blue. E through H are from a donor with acute lung injury: E: combined image. F: tomato lectin, red. G: HTII-280, green. H: DAPI, blue. White arrows point to cells that appear doubly labeled with the apical type II cell marker HTII-280 and the type I cell marker tomato lectin.