Schematic of the method of determining the slope ratio (SR) of a single point along the maximal expiratory flow-volume (MEFV) curve. Example represents an MEFV curve from a healthy female subject in the control (CON) group. The same procedure was repeated at each point of interest along each subject’s MEFV curve. Tan, tangent; V̇, flow; Vexp, volume remaining to be expired; ΔV̇, change in flow; ΔVexp, change in volume.