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. 2019 Aug 21;317(4):R588–R596. doi: 10.1152/ajpregu.00114.2019

Table 2.

Pulmonary function data

CON (n = 20)
PRE (n = 19)
BPD (n = 25)
Absolute values %Predicted Z-score Absolute values %Predicted Z-score Absolute values %Predicted Z-score
Spirometry
    FVC, liters 4.9 ± 0.2 103 ± 2 0.34 ± 0.16 4.7 ± 0.2 95 ± 3 −0.17 ± 0.21 4.3 ± 0.3 90 ± 3* −0.54 ± 0.24*
    FEV1, liters 3.9 ± 0.2 103 ± 2 −0.13 ± 0.15 3.7 ± 0.2 92 ± 2* −0.90 ± 0.26 3.1 ± 0.2* 82 ± 4* −1.61 ± 0.29*
    FEV1/FVC 81 ± 1 95 ± 1 −0.76 ± 0.16 78 ± 2 92 ± 2 −1.11 ± 0.23 74 ± 2* 85 ± 3* −1.62 ± 0.26*
    PEF, l × s−1 9.1 ± 0.4 112 ± 2 7.6 ± 0.4* 88 ± 3* 6.5 ± 0.4* 78 ± 4*
    FEF25, l × s−1 8.0 ± 0.3 106 ± 3 6.3 ± 0.4* 78 ± 4* 5.0 ± 0.4* 65 ± 4*
    FEF50, l × s−1 4.7 ± 0.2 85 ± 4 3.9 ± 0.3 70 ± 5 3.1 ± 0.3* 58 ± 5*
    FEF75, l × s−1 2.0 ± 0.1 88 ± 6 −0.16 ± 0.19 1.7 ± 0.2 71 ± 6 −0.95 ± 0.24 1.4 ± 0.1* 60 ± 6* −1.41 ± 0.28*
    FEF25–75, l × s−1 3.9 ± 0.2 94 ± 3 −0.46 ± 0.15 3.3 ± 0.3 75 ± 5* −1.33 ± 0.24* 2.7 ± 0.2* 63 ± 5* −1.96 ± 0.28*
Lung volumes
    TLC, liters 6.2 ± 0.2 103 ± 2 6.3 ± 0.3 102 ± 3 5.9 ± 0.3 102 ± 2
    IC, liters 3.1 ± 0.1 108 ± 4 3.1 ± 0.1 100 ± 4 2.7 ± 2 95 ± 4*
    FRC, liters 3.1 ± 0.1 99 ± 4 3.3 ± 0.2 107 ± 5 3.2 ± 0.2 109 ± 4
    ERV, liters 1.8 ± 0.1 109 ± 4 1.7 ± 0.1 100 ± 6 1.6 ± 0.1 96 ± 6
    RV, liters 1.2 ± 0.1 87 ± 6 1.5 ± 0.1 111 ± 9 1.6 ± 0.1 126 ± 9*

All values are expressed as means ± SD; n, number of subjects. BPD, bronchopulmonary dysplasia; CON, control; ERV, expiratory reserve volume; FEV1, forced expiratory volume in 1 s; FEF25, forced expiratory flow at 25% of FVC; FEF50, forced expiratory flow at 50% of FVC; FEF75, forced expiratory flow at 75% of FVC; FEF25–75, average forced expiratory flow from 25 to 75% of FVC; FRC, functional residual capacity; FVC, forced vital capacity; IC, inspiratory capacity; PEF, peak expiratory flow; PRE, preterm without bronchopulmonary dysplasia; RV, residual volume; TLC, total lung capacity.

*

Statistically significant difference from CON, P < 0.05;

statistically significant difference between PRE and BPD, P < 0.05.