Table 2.
CON (n = 20) |
PRE (n = 19) |
BPD (n = 25) |
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Absolute values | %Predicted | Z-score | Absolute values | %Predicted | Z-score | Absolute values | %Predicted | Z-score | |
Spirometry | |||||||||
FVC, liters | 4.9 ± 0.2 | 103 ± 2 | 0.34 ± 0.16 | 4.7 ± 0.2 | 95 ± 3 | −0.17 ± 0.21 | 4.3 ± 0.3 | 90 ± 3* | −0.54 ± 0.24* |
FEV1, liters | 3.9 ± 0.2 | 103 ± 2 | −0.13 ± 0.15 | 3.7 ± 0.2 | 92 ± 2* | −0.90 ± 0.26 | 3.1 ± 0.2*† | 82 ± 4* | −1.61 ± 0.29* |
FEV1/FVC | 81 ± 1 | 95 ± 1 | −0.76 ± 0.16 | 78 ± 2 | 92 ± 2 | −1.11 ± 0.23 | 74 ± 2* | 85 ± 3* | −1.62 ± 0.26* |
PEF, l × s−1 | 9.1 ± 0.4 | 112 ± 2 | 7.6 ± 0.4* | 88 ± 3* | 6.5 ± 0.4* | 78 ± 4* | |||
FEF25, l × s−1 | 8.0 ± 0.3 | 106 ± 3 | 6.3 ± 0.4* | 78 ± 4* | 5.0 ± 0.4*† | 65 ± 4*† | |||
FEF50, l × s−1 | 4.7 ± 0.2 | 85 ± 4 | 3.9 ± 0.3 | 70 ± 5 | 3.1 ± 0.3* | 58 ± 5* | |||
FEF75, l × s−1 | 2.0 ± 0.1 | 88 ± 6 | −0.16 ± 0.19 | 1.7 ± 0.2 | 71 ± 6 | −0.95 ± 0.24 | 1.4 ± 0.1* | 60 ± 6* | −1.41 ± 0.28* |
FEF25–75, l × s−1 | 3.9 ± 0.2 | 94 ± 3 | −0.46 ± 0.15 | 3.3 ± 0.3 | 75 ± 5* | −1.33 ± 0.24* | 2.7 ± 0.2*† | 63 ± 5* | −1.96 ± 0.28* |
Lung volumes | |||||||||
TLC, liters | 6.2 ± 0.2 | 103 ± 2 | 6.3 ± 0.3 | 102 ± 3 | 5.9 ± 0.3 | 102 ± 2 | |||
IC, liters | 3.1 ± 0.1 | 108 ± 4 | 3.1 ± 0.1 | 100 ± 4 | 2.7 ± 2 | 95 ± 4* | |||
FRC, liters | 3.1 ± 0.1 | 99 ± 4 | 3.3 ± 0.2 | 107 ± 5 | 3.2 ± 0.2 | 109 ± 4 | |||
ERV, liters | 1.8 ± 0.1 | 109 ± 4 | 1.7 ± 0.1 | 100 ± 6 | 1.6 ± 0.1 | 96 ± 6 | |||
RV, liters | 1.2 ± 0.1 | 87 ± 6 | 1.5 ± 0.1 | 111 ± 9 | 1.6 ± 0.1 | 126 ± 9* |
All values are expressed as means ± SD; n, number of subjects. BPD, bronchopulmonary dysplasia; CON, control; ERV, expiratory reserve volume; FEV1, forced expiratory volume in 1 s; FEF25, forced expiratory flow at 25% of FVC; FEF50, forced expiratory flow at 50% of FVC; FEF75, forced expiratory flow at 75% of FVC; FEF25–75, average forced expiratory flow from 25 to 75% of FVC; FRC, functional residual capacity; FVC, forced vital capacity; IC, inspiratory capacity; PEF, peak expiratory flow; PRE, preterm without bronchopulmonary dysplasia; RV, residual volume; TLC, total lung capacity.
Statistically significant difference from CON, P < 0.05;
statistically significant difference between PRE and BPD, P < 0.05.