Fig. 4.
Individual heart failure with reduced ejection fraction (HFrEF) data pre- and posttraining during the 2nd minute of mild (0 load) cycling (A; left) and moderate load [50% of peak oxygen uptake (V̇o2peak) adjusted for 1-leg] cycling (A, right). Muscle sympathetic nerve activity (MSNA; B) burst frequency (means ± SE) is reduced after exercise training during 1st and 2nd minute of mild- but not moderate-intensity 1-leg cycling exercise in HFrEF patients (pretraining, closed triangles; posttraining, open triangles; n = 16) but is still higher than in healthy control subjects (closed circles; n = 18). Effect of group, P < 0.001; *P = 0.04; HFrEF pre- vs. posttraining; **P < 0.001 HFrEF vs. controls.