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. 2019 Oct 22;10:2476. doi: 10.3389/fimmu.2019.02476

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Copyright © 2019 van Eijk, Hillaire, Rimmelzwaan, Rynkiewicz, White, Hartshorn, Hessing, Koolmees, Tersteeg, van Es, Meijerhof, Huckriede and Haagsman.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Aggregation of IAV particles by hSP-D and iSP-D. IAV particles [strain A/Aichi/68 (H3N2)] were suspended in buffer, mixed at t = 0 with 4.0 μg/ml iSP-D or hSP-D (control: virus only). The continuously stirred mixture was monitored for light transmission during 12 min and results are expressed as % of light transmission at t = 0. Measurements were performed five times and values are mean ± SEM. Statistical analysis was carried out by the two-tailed paired Student's t-test. *p < 0.05 (iSP-D vs. hSP-D).