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. 2019 Aug 1;317(4):G518–G530. doi: 10.1152/ajpgi.00172.2019

Fig. 5.

Fig. 5.

Phenotype of sodium-dependent multivitamin transporter (SMVT)-inducible, conditional knockout (icKO) mice following administration of antibiotics (ABX). A: Kaplan-Meier survival curve for intestine-specific SMVT-icKO mice after rescue with antibiotics treatment (n = 8). Blue dotted line indicates SMVT-icKO mice treated with antibiotic and red dotted line is for nontreated SMVT-icKO mice. Black solid line is for control littermates. B: plot showing clear recovery from weight loss of antibiotic-treated SMVT-icKO mice compared with nontreated SMVT-icKO and their sex-matched control littermates starting from the 6th day after tamoxifen injection [n = 8; statistical significance (**P < 0.01) is calculated using unpaired Student’s t test]. C: representative photographs and bar diagram showing recovery in length of large intestine (i) and colon length (ii) of SMVT-icKO mice after administration of antibiotic cocktail. Colonic length of each group of mice is presented as box and dot-whisker plots from four separate sets of mice, and statistical significance (*P < 0.05) is calculated with the Mann-Whitney test.