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. 2019 Aug 14;317(4):G447–G452. doi: 10.1152/ajpgi.00158.2019

Table 1.

Baseline patient demographics stratified by AKI status

No AKI Development AKI Development P
n 85 13
Age 54.02 (8.38) 55.77 (8.32) 0.49
Gender, n (%) male 46 (54) 6 (46) 0.78
Race, n (%) white 77 (91) 12 (92) 0.52
Etiology of cirrhosis, n (%)
    HCV 10 (12) 3 (23)
    HCV + alcohol 16 (19) 1 (8)
    NASH 29 (34) 5 (38) 0.75
    Alcohol 19 (22) 3 (23)
    Other 11 (13) 1 (8)
Infection on admission, n (%) 18 (21) 5 (38) 0.18
History of ascites, n (%) 61 (72) 12 (92) 0.17
History of HE, n (%) 58 (68) 11 (85) 0.19
History of PHTN bleed, n (%) 13 (15) 1 (8) 0.69
DM, n (%) 35 (41) 6 (46) 0.77
HTN, n (%) 29 (34) 5 (38) 0.76
MAP 84.08 (12.90) 80.38 (11.78) 0.33
Baseline creatinine, mg/dL 0.94 (0.35) 0.99 (0.30) 0.60
Baseline eGFR, mL·min−1·1.73 m−2* 86.06 (26.86) 76.77 (21.34) 0.23
Admit creatinine, mg/dL 0.98 (0.38) 1.08 (0.41) 0.39
Admit eGFR, mL·min−1·1.73 m−2* 82.82 (27.01) 73.62 (26.82) 0.26
Admit sodium, mmol/L 133.56 (12.00) 132.54 (6.62) 0.65
Admit albumin, g/dL 2.94 (0.62) 2.51 (0.57) 0.02
Admit total bilirubin, mg/dL 4.19 (4.95) 2.84 (2.60) 0.14
Admit WBC, 109/L 6.98 (4.50) 7.92 (3.84) 0.48
Admit INR 1.65 (0.58) 1.61 (0.57) 0.84
CTP score 9.31 (2.10) 9.77 (1.88) 0.45
CTP class, n (%)
    A 10 (12) 0 (0)
    B 33 (39) 6 (46) 0.57
    C 42 (49) 7 (54)
MELD-sodium score 19.27 (6.22) 20.23 (6.37) 0.61

AKI, acute kidney injury; CTP, Child Turcotte Pugh; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; HCV, hepatitis C; HE, hepatic encephalopathy; HTN, hypertension; INR, international normalized ratio; MAP, mean arterial pressure; MELD, Model for Endstage Liver Disease; NASH, nonalcoholic steatohepatitis; PTHN, portal hypertension; WBC, white blood cell.

*

Based on Chronic Kidney Disease Epidemiology Collaboration creatinine equation (24).