Table 1.
No AKI Development | AKI Development | P | |
---|---|---|---|
n | 85 | 13 | |
Age | 54.02 (8.38) | 55.77 (8.32) | 0.49 |
Gender, n (%) male | 46 (54) | 6 (46) | 0.78 |
Race, n (%) white | 77 (91) | 12 (92) | 0.52 |
Etiology of cirrhosis, n (%) | |||
HCV | 10 (12) | 3 (23) | |
HCV + alcohol | 16 (19) | 1 (8) | |
NASH | 29 (34) | 5 (38) | 0.75 |
Alcohol | 19 (22) | 3 (23) | |
Other | 11 (13) | 1 (8) | |
Infection on admission, n (%) | 18 (21) | 5 (38) | 0.18 |
History of ascites, n (%) | 61 (72) | 12 (92) | 0.17 |
History of HE, n (%) | 58 (68) | 11 (85) | 0.19 |
History of PHTN bleed, n (%) | 13 (15) | 1 (8) | 0.69 |
DM, n (%) | 35 (41) | 6 (46) | 0.77 |
HTN, n (%) | 29 (34) | 5 (38) | 0.76 |
MAP | 84.08 (12.90) | 80.38 (11.78) | 0.33 |
Baseline creatinine, mg/dL | 0.94 (0.35) | 0.99 (0.30) | 0.60 |
Baseline eGFR, mL·min−1·1.73 m−2* | 86.06 (26.86) | 76.77 (21.34) | 0.23 |
Admit creatinine, mg/dL | 0.98 (0.38) | 1.08 (0.41) | 0.39 |
Admit eGFR, mL·min−1·1.73 m−2* | 82.82 (27.01) | 73.62 (26.82) | 0.26 |
Admit sodium, mmol/L | 133.56 (12.00) | 132.54 (6.62) | 0.65 |
Admit albumin, g/dL | 2.94 (0.62) | 2.51 (0.57) | 0.02 |
Admit total bilirubin, mg/dL | 4.19 (4.95) | 2.84 (2.60) | 0.14 |
Admit WBC, 109/L | 6.98 (4.50) | 7.92 (3.84) | 0.48 |
Admit INR | 1.65 (0.58) | 1.61 (0.57) | 0.84 |
CTP score | 9.31 (2.10) | 9.77 (1.88) | 0.45 |
CTP class, n (%) | |||
A | 10 (12) | 0 (0) | |
B | 33 (39) | 6 (46) | 0.57 |
C | 42 (49) | 7 (54) | |
MELD-sodium score | 19.27 (6.22) | 20.23 (6.37) | 0.61 |
AKI, acute kidney injury; CTP, Child Turcotte Pugh; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; HCV, hepatitis C; HE, hepatic encephalopathy; HTN, hypertension; INR, international normalized ratio; MAP, mean arterial pressure; MELD, Model for Endstage Liver Disease; NASH, nonalcoholic steatohepatitis; PTHN, portal hypertension; WBC, white blood cell.
Based on Chronic Kidney Disease Epidemiology Collaboration creatinine equation (24).