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. 2019 Aug 23;317(4):H793–H810. doi: 10.1152/ajpheart.00215.2019

Fig. 2.

Fig. 2.

Gravin-t/t mice show decreased blood pressure in response to high-fat diet (HFD). HFD-fed Gravin-t/t mice showed reduced systolic blood pressure (A), reduced diastolic blood pressure (B), and reduced mean blood pressure (C) as compared with wild-type (WT) mice measured at 16 wk of age. No difference in heart rate (D) was observed. Results are presented as mean ± SE. n = 8 [(WT normal diet (ND)], n = 7 (WT HFD), n = 8 (Gravin-t/t ND), and n = 7 (Gravin-t/t HFD) (A); n = 8 (WT ND), n = 8 (WT HFD), n = 8 (Gravin-t/t ND), and n = 7 (Gravin-t/t HFD) (B); n = 8 (WT ND), n = 8 (WT HFD), n = 7 (Gravin-t/t ND), and n = 7 (Gravin-t/t HFD) (C); and n = 9 (WT ND), n = 7 (WT HFD), n = 7 (Gravin-t/t ND), and n = 7 (Gravin-t/t HFD) (D). **P < 0.01, and ***P < 0.001. Comparisons between two groups were determined by an unpaired two-tailed Student’s t test, and comparisons between multiple groups were determined by one-way ANOVA followed by post hoc Tukey test.