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. 2019 Aug 14;317(4):F1034–F1046. doi: 10.1152/ajprenal.00166.2019

Fig. 2.

Fig. 2.

Biomarkers of kidney injury. Urine and blood samples were collected at 4 and 8 wk after streptozotocin (STZ) injection, and ELISA was used to determine levels of urinary albumin, creatinine, neutrophil gelatinase-associated lipocalin (NGAL), and kidney injury molecule-1 (KIM-1) as well as plasma NGAL. A: urinary albumin-to-creatinine ratios (UACRs) were determined by normalizing urinary albumin to creatinine levels. B–D: urinary NGAL (B and C) and KIM-1 (D) levels were also normalized to levels of creatinine (Crt). WT, wild type; KO, knockout. *P ≤ 0.05; **P ≤ 0.01; ****P ≤ 0.0001.