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. 2019 Aug 7;317(4):F1010–F1021. doi: 10.1152/ajprenal.00028.2019

Fig. 4.

Fig. 4.

A: raw tracings of changes in total renal sympathetic activity (RSNA), mean arterial pressure (MAP), and heart rate (HR) to intravenous infusion of glucagon-like peptide-1 (GLP-1) in a normal rat with intact renal nerves. B: raw tracings of changes in efferent renal nerve activity (ERNA), MAP, and HR to intravenous infusion of GLP-1 in a normal rat after the renal nerves were sectioned (proximal end recording). C: raw tracings of changes in afferent renal nerve activity (ARNA), MAP, and HR to intravenous infusion of GLP-1 in a normal rat after the renal nerves were sectioned (distal end recording). Magnified tracings at baseline (a) and during GLP-1 infusion (b) with short timescale recordings are shown. D and E: baseline MAP and HR in the three groups of normal rats (total RSNA, ERNA, and ARNA recording groups). F: summary data for the effect of GLP-1 on changes in total RSNA, ERNA, and ARNA. G and H: summary data for the effect of GLP-1 on changes in MAP and HR in the three groups of normal rats (total RSNA, ERNA, and ARNA recording groups). n = 5–6. *P < 0.05 and **P < 0.01 vs. normal rats with intact renal nerves. bpm, beats/min; BP, blood pressure; Int, integrated.