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. 2019 Aug 7;317(4):F1010–F1021. doi: 10.1152/ajprenal.00028.2019

Table 1.

Hemodynamic changes during intravenous infusion of glucagon-like peptide-1

  Normal Total Renal Denervation (Unilateral) Afferent Renal Nerve Denervation (Bilateral)
n 5 6 5
Mean arterial pressure, mmHg
    Baseline 99 ± 3 96 ± 3 98 ± 2
    10 min 115 ± 4 104 ± 2* 107 ± 3*
    20 min 120 ± 4 106 ± 2 110 ± 4
    30 min 123 ± 3 105 ± 3*§ 109 ± 3
    40 min 108 ± 6* 99 ± 3 106 ± 2
    50 min 97 ± 5 97 ± 4 95 ± 2
    60 min 101 ± 3 95 ± 3 93 ± 2
Heart rate, beats/min
    Baseline 324 ± 10 340 ± 12 339 ± 8
    10 min 367 ± 6 339 ± 12 330 ± 13
    20 min 416 ± 11 353 ± 12§ 339 ± 17§
    30 min 443 ± 10 367 ± 11§ 349 ± 16§
    40 min 435 ± 10 373 ± 13*§ 354 ± 14§
    50 min 393 ± 25 371 ± 12* 357 ± 10
    60 min 382 ± 20 364 ± 10 351 ± 8

Values are means ± SE; n = 5–6 for each group of rats.

*

P < 0.05 and

P < 0.01 compared with baseline;

P < 0.05 and

§

P < 0.01 compared with the normal group.