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. 2019 Oct 14;10(10):700. doi: 10.3390/mi10100700

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Examples of commercially available OOC systems with stretch and strain stimuli. (A) Microfluidic device was inserted to the MechanoCulture B1 system from CellScale Inc. to provide the biaxial mechanical stretch stimulation and evaluate its effect on cell alignment. Reproduced with permission from Reference [61]. (B) Porcine heart valves were positioned in the biaxial mechanical tester (BioTester, CellScale Inc.) to characterize heterogeneity of heart valve leaflet. Reproduced with permission from Reference [62].