Table 1.
Demographic, clinical and pathological data
| Characteristic | Total Cohort | % | PRAE group pt. | % | No-PRAE group pt. | % |
|---|---|---|---|---|---|---|
| Patients n | 64 | 100% | 30 | 47% | 34 | 53% |
| Sex Male | 29 | 45.3% | 11 | 37% | 18 | 53% |
| Female | 35 | 54.7% | 19 | 63% | 16 | 47% |
| Age Median | 67.5 | 65.7 | 66.2 | |||
| Range | 19-81 | 19-81 | 38-80 | |||
| Site Right | 30 | 46.8% | 14 | 46.6% | 16 | 47% |
| Left | 34 | 53.2% | 16 | 53.4% | 18 | 53% |
| Median Clinical Size (range) | 10 cm (8-17) | 11 cm (8-17) | 8 cm (8-16) | |||
| PNS | ||||||
| Anemia | 19 | 29.6% | 9 | 30% | 10 | 34% |
| Fever | 20 | 31.2% | 8 | 66% | 12 | 35% |
| Asthenia | 13 | 20.3% | 7 | 23% | 6 | 18% |
| Weight Loss | 9 | 14% | 4 | 13% | 5 | 14% |
| Hypertension | 3 | 4.7% | 3 | 10% | 0 | 0% |
| Ascites/Aedema | 2 | 3.1% | 1 | 3% | 1 | 3% |
| cT Staging | ||||||
| cT2b | 23 | 36% | 11 | 37% | 11 | 33% |
| cT3a | 27 | 42% | 16 | 53% | 12 | 35% |
| cT3b | 9 | 14% | 0 | 0% | 9 | 26% |
| cT4 | 5 | 7% | 3 | 10% | 2 | 6% |
| cN Staging | ||||||
| cN0 | 29 | 44% | 12 | 40% | 15 | 45% |
| cN1 | 27 | 42% | 14 | 47% | 14 | 41% |
| cN2 | 9 | 14% | 4 | 13% | 5 | 14% |
| cM Staging | ||||||
| cM0 | 41 | 64% | 20 | 67% | 21 | 62% |
| cM1 | 23 | 36% | 10 | 33% | 13 | 38% |
| pT Staging | ||||||
| pT0 | 6 | 9% | 2 | 7% | 4 | 12% |
| pT2 | 17 | 26% | 11 | 37% | 4 | 35% |
| pT3 | 40 | 63% | 16 | 53% | 26 | 59% |
| pT4 | 1 | 2% | 1 | 3% | 0 | 0% |
| Grading | ||||||
| G0 | 6 | 9% | 2 | 7% | 4 | 12% |
| G1 | 4 | 6% | 2 | 7% | 1 | 3% |
| G2 | 18 | 28% | 6 | 20% | 10 | 29% |
| G3 | 30 | 47% | 16 | 53% | 14 | 41% |
| G4 | 9 | 14% | 4 | 13% | 5 | 15% |
| pN Staging | ||||||
| pNx | 16 | 25% | 9 | 30% | 7 | 20% |
| pN0 | 37 | 58% | 14 | 47% | 23 | 68% |
| pN1 | 11 | 17% | 7 | 23% | 4 | 12% |
| Margins | ||||||
| R0 | 59 | 92% | 28 | 93% | 31 | 91% |
| R1 | 5 | 2 | 7% | 3 | 9% | |
| 8% | ||||||
| PRAE material | ||||||
| Gelatine Sponge | 26 | 41% | 26 | 87% | n.a | n.a |
| Polyvinyl Alchool | 12 | 19% | 12 | 40% | n.a | n.a |
| Metallic Spirals | 12 | 19% | 12 | 40% | n.a | n.a |
| PIS | 26/30 | 87% | 26 | 87% | n.a | n.a |
| Median Time P-t-S (range) | 21 h | 21 h (14-30) | n.a | |||
| (14-30) | ||||||
| Histotype | ||||||
| RCC | 50 | 78.2% | 22 | 74% | 28 | 82% |
| Oncocytoma | 3 | 4.7% | 1 | 3% | 2 | 6% |
| Cromophobe | 4 | 6.3% | 3 | 10% | 1 | 3% |
| Papillary | 1 | 1.5% | 1 | 3% | 0 | 0% |
| Solitary Fibrous Tumor | 1 | 1.5% | 1 | 3% | 0 | 0% |
| KS | 4 | 6.3% | 2 | 7% | 2 | 6% |
| TCC | 1 | 1.5% | 0 | 0% | 1 | 3% |
| Median Blood loss (range) | 325 cc (50-1000) | 250 cc (50-500) | 400 cc (50-1000) | |||
| Median Surgical Time (range) | 220 min (90-390) | 205 min (90-390) | 240 min (130-390) | |||
| Transfusion Rate | 23/64 | 36% | 9 | 30% | 14 | 41% |
| Intraoperative Transfusion Rate | 13/64 | 20% | 4 | 13% | 9 | 26% |
| Hospital Transfusion Rate | 17/64 | 26% | 7 | 23% | 10 | 29% |
| Median Hospital Stay (range) | 8 d (5-20) | 8 d (6-20) | 8 d (5-15) | |||
| Int. Care Unit stay | 12 | 19% | 8 | 27% | 4 | 12% |
Abbreviation: PNS= para neoplastic syndrome; PIS=post infarction Syndrome; P-t-S= PRAE to Surgery; RCC= renal cell carcinoma; SFT= Solitary Fibrous Tumor; KS= Kidney’s Sarcoma; TCC= transitional cell carcinoma.