Table 2.
Metabolites that showed significantly lower levels in plasma of men receiving a daily addition of SeQ10 for 18 months as compared with the controls, the placebo-treated men.
| Metabolite | p-Value | VIP (OPLS-DA) |
|---|---|---|
| Decreased in SeQ10 group | ||
| Alanine | 0.001 | 1.79 |
| Alanine-3-cyano | 0.016 | 1.62 |
| Arachidonic acid | NS | 1.30 |
| Aspartic acid | 0.017 | 1.65 |
| Butyric acid, 2-amino | NS | 1.16 |
| Cysteine | 0.048 | 1.05 |
| Fucose | NS | 1.21 |
| Glutamic acid | 0.022 | 1.60 |
| Glycine | 0.010 | 1.50 |
| Isoleucine | 0.031 | 1.49 |
| Leucine | NS | 1.45 |
| Methionine | 0.030 | 1.51 |
| Myo-inositol | 0.022 | 1.42 |
| Ornithine-1,5-lactam | 0.013 | 1.29 |
| Phenylalanine | NS | 1.25 |
| Proline-4-hydroxy | 0.026 | 1.39 |
| Salicylic acid | NS | 1.34 |
| Serine | 0.032 | 1.44 |
| Threonine | 0.049 | 1.36 |
Note: No metabolite showed significantly higher levels in SeQ10 men; Note: VIP: Variables’ Importance to the Projection. Note: T-tests were used in the statistical evaluation. Note: NS: Not significant.