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. 2019 Oct 4;55(10):673. doi: 10.3390/medicina55100673

Table 3.

Subgroup analysis for disease-free survival in colorectal cancer.

Number of Subset Fixed Effect
(95% CI)
Heterogeneity Test
(p-Value)
Random Effect
(95% CI)
Egger’s Test
(p-Value)
Overall 11 2.209 (1.883, 2.591) 0.129 2.345 (1.879, 2.926) 0.020
Tumor stage
Stage III 6 2.246 (1.795, 2.809) 0.091 2.451 (1.719, 3.494) 0.165
High mLNR criteria
mLNR < 0.2 4 1.976 (1.425, 2.740) 0.056 2.878 (1.401, 5.912) 0.061
mLNR ≤ 0.2 7 2.131 (1.667, 2.723) 0.081 2.497 (1.706, 3.657) 0.015
mLNR ≥ 0.2 7 2.287 (1.905, 2.747) 0.324 2.322 (1.885, 2.861) 0.160
Colon 4 2.496 (1.917, 3.249) 0.495 2.496 (1.917, 3.249) 0.490
Rectum 2 2.158 (1.645, 2.831) 0.060 2.730 (1.226, 6.076) NA

CI, confidence interval; mLNR, metastatic lymph node ratio; NA, not applicable. Colon cancer represent mLNR > 0.2, and rectal cancer present mLNR = 0.2, respectively.