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. 2019 Oct 12;16(20):3873. doi: 10.3390/ijerph16203873

Table 2.

Microbial Domains Comparisons [48].

Property Bacteria Archaea Fungi
Cell Membrane Made up of peptidoglycan and lipids are linked via ester molecule, Made up of pseudo-peptidoglycan and lipids are linked via ether molecule Made up of different structures and lipids are linked via ester molecule
Gene Structure and Configuration Chromosomes are circular, translation and transcription are unique Chromosomes are circular, translation and transcription are similar to eukaryotes (fungi) Chromosomes are multiple and linear, translation and transcription are similar to archaea
Structure of Internal Cell The nucleus or organelles has no membrane bound The nucleus or organelles has no membrane bound There is membrane bound nucleus and organelles
Metabolic Reaction There are several, including aerobic and anaerobic respiration, photosynthetic, autotrophic reactions and fermentation There are several with methanogenic reaction specifically unique to this domain Cellular respiration, fermentation and photosynthetic reaction
Reproduction Reproduction is asexual and transfer of genes is horizontal Reproduction is asexual and transfer of genes is horizontal Reproduction is sexual and asexual