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Effect of the administration of sodium saccharine in rats (n = 10) at 2.5, 5, and 10 mg/kg.b.w. at 0 time and after 60 and 120 days on (a) AST, (b) ALT, (c) uric acid, and (d) creatinine. Comparison between the groups was made by the one-way analysis of variance (ANOVA) with mean ± SEM. Significant (*) at p < 0.05.
