Table 1.
Univariate and multivariate analysis of factors associated with DFS of HCC patients
| Variables | Hazard ratio (95% CI) | P value |
|---|---|---|
| Univariate analysis | ||
| Panx1 (low, moderate vs high) | 1.824 (1.187-2.801) | 0.006 |
| Gender (male vs female) | 1.446 (0.342-6.112) | 0.616 |
| Age (>50 vs ≤50) | 1.188 (0.534-2.647) | 0.673 |
| HBV (positive vs negative) | 0.383 (0.051-2.854) | 0.349 |
| Tumor size (>5cm vs ≤5cm) | 3.082 (1.423-6.674) | 0.004 |
| Liver cirrhosis (yes vs no) | 0.544 (0.219-1.351) | 0.189 |
| Microvascular involvement (positive vs negative) | 4.803 (2.223-10.380) | <0.001 |
| Differentiation (Poorly vs well+moderately) | 2.721 (1.088-6.805) | 0.032 |
| TNM stage (III vs I-II) | 5.144 (1.938-13.655) | 0.001 |
| Lymph node metastasis (yes vs no) | 1.494 (0.563-4.729) | 0.102 |
| AFP (>20ng/ml vs ≤20ng/m) | 0.893 (0.360-2.212) | 0.806 |
| Multivariate analysis | ||
| Panx1 (low, moderate vs high) | 2.344 (1.473-3.730) | <0.001 |
| TNM stage (III vs I-II) | 4.029 (1.476-10.999) | 0.007 |
| Microvascular involvement (positive vs negative) | 3.426(1.451-8.090) | 0.005 |
P<0.05 was considered statistically significant