Table 1.
Demographic and tumor characteristics of patients with node positive gastric cancer
| Subgroup | P value | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| All Patients | N1 | N2 | N3a | N3b | |||||||
| n=8475 | n=2738 | n=2493 | n=2252 | n=992 | |||||||
| Characteristic | No. | % | No. | % | No. | % | No. | % | No. | % | |
| Sex | 0.016 | ||||||||||
| male | 5404 | 63.8 | 1775 | 64.8 | 1613 | 64.7 | 1426 | 63.3 | 590 | 59.5 | |
| female | 3071 | 36.2 | 963 | 35.2 | 880 | 35.3 | 826 | 36.7 | 402 | 40.5 | |
| Age | <0.001 | ||||||||||
| <60 | 2924 | 34.5 | 846 | 30.9 | 843 | 33.8 | 876 | 38.9 | 359 | 36.2 | |
| ≥60 | 5551 | 65.5 | 1892 | 69.1 | 1650 | 66.2 | 1376 | 61.1 | 633 | 63.8 | |
| Race | <0.001 | ||||||||||
| White | 5629 | 66.4 | 1856 | 67.8 | 1681 | 67.4 | 1453 | 64.5 | 639 | 64.4 | |
| African American | 1170 | 13.8 | 381 | 13.9 | 364 | 14.6 | 301 | 13.4 | 124 | 12.5 | |
| Others | 1676 | 19.8 | 501 | 18.3 | 448 | 18.0 | 498 | 22.1 | 229 | 23.1 | |
| Location | <0.001 | ||||||||||
| Cardia, NOS | 2198 | 15.9 | 864 | 31.6 | 711 | 28.5 | 474 | 21.0 | 149 | 15.0 | |
| Fundus of stomach | 255 | 3.0 | 76 | 2.8 | 92 | 3.7 | 56 | 2.5 | 31 | 3.1 | |
| Body of stomach | 661 | 8.0 | 202 | 7.4 | 185 | 7.4 | 180 | 8.0 | 94 | 9.5 | |
| Gastric antrum | 2118 | 25.0 | 652 | 23.8 | 631 | 25.3 | 596 | 26.5 | 239 | 24.1 | |
| Pylorus | 403 | 4.8 | 130 | 4.7 | 129 | 5.2 | 117 | 5.2 | 27 | 2.7 | |
| Lesser curvature of stomach NOS | 952 | 11.2 | 295 | 10.8 | 248 | 9.9 | 286 | 12.7 | 123 | 12.4 | |
| Greater curvature of stomach NOS | 402 | 4.7 | 128 | 4.7 | 108 | 4.3 | 111 | 4.9 | 55 | 5.5 | |
| Overlapping lesion of stomach | 756 | 8.9 | 174 | 6.4 | 182 | 7.3 | 245 | 10.9 | 155 | 15.6 | |
| Stomach, NOS | 730 | 8.6 | 217 | 7.9 | 207 | 8.3 | 187 | 8.3 | 119 | 12.0 | |
| Pathological grading | <0.001 | ||||||||||
| High/ Moderate | 1985 | 23.4 | 853 | 31.2 | 611 | 24.5 | 404 | 17.9 | 117 | 11.8 | |
| Poor/ Anaplastic | 6171 | 72.8 | 1731 | 63.2 | 1813 | 72.7 | 1782 | 79.1 | 845 | 85.2 | |
| Unknown | 319 | 3.8 | 154 | 5.6 | 69 | 2.8 | 66 | 2.9 | 30 | 3.0 | |
| Histotype | <0.001 | ||||||||||
| Adenocarcinoma | 5962 | 70.3 | 2110 | 77.1 | 1825 | 73.2 | 1474 | 65.5 | 553 | 55.7 | |
| Mucinous /Signet ring cell | 2513 | 29.7 | 628 | 22.9 | 668 | 26.8 | 778 | 34.5 | 439 | 44.3 | |
| pT stage | <0.001 | ||||||||||
| T1 | 581 | 6.9 | 373 | 13.6 | 159 | 6.4 | 41 | 1.8 | 8 | 0.8 | |
| T2 | 786 | 9.3 | 412 | 15.0 | 227 | 9.1 | 122 | 5.4 | 25 | 2.5 | |
| T3 | 3596 | 42.4 | 1090 | 39.8 | 1169 | 46.9 | 1007 | 44.7 | 330 | 33.3 | |
| T4 | 3460 | 40.8 | 820 | 29.9 | 934 | 37.5 | 1078 | 47.9 | 628 | 63.3 | |
| Tx | 52 | 0.6 | 43 | 1.6 | 4 | 0.2 | 4 | 0.2 | 1 | 0.1 | |
| No. of LNs dissected | 17.89(9-23) | 13.18(5-18) | 15.91(8-20) | 19.67(13-24) | 31.87(22-38) | <0.001 | |||||
| No. of positive LNs | 7.19(2-10) | 1.40(1-2) | 4.26(3-5) | 10.14(8-12) | 23.80(18-27) | <0.001 | |||||