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. 2019 Sep 7;10(23):5646–5653. doi: 10.7150/jca.30979

Table 3.

Univariate and multivariate survival analyses for evaluating the influence of the number of retrieved LNs influencing GCSS in node positive gastric cancer patients.

Univariate analysis Multivariate analysis
Variable 5-year GCCS Log rank χ2 test P HR(95%CI) P
Sex 3.059 0.08
Male 30.4%
Female 28.5%
Age 23.923 <0.001 <0.001
<60 32.0% Reference
≥60 28.4% 1.295(1.221-1.373)
Race 51.463 <0.001 <0.001
White 27.6% Reference
African American 28.2% 1.042(0.960-1.131)
Others 37.5% 0.809(0.751-0.871)
Location 72.114 <0.001 0.0251
Cardia, NOS 26.1% Reference
Fundus of stomach 31.4% 0.827(0.700-0.978)
Body of stomach 30.5% 0.769(0.687-0.861)
Gastric antrum 32.6% 0.778(0.718-0.842)
Pylorus 29.7% 0.857(0.748-0.982)
Lesser curvature of stomach NOS 37.1% 0.693(0.625-0.768)
Greater curvature of stomach NOS 31.2% 0.812(0.707-0.931)
Overlapping lesion of stomach 23.3% 0.860(0.774-0.955)
Stomach, NOS 26.6% 0.891(0.801-0.992)
Pathological grading 98.930 <0.001 <0.001
High/ Moderate 37.9% Reference
Poor/ Anaplastic 27.4% 1.156(1.077-1.241)
Unknown 21.7% 1.186(1.021-1.377)
Histotype 45.168 <0.001 0.060
Adenocarcinoma 32.1% Reference
Mucinous/signet ring cell 24.0% 1.061(0.998-1.129)
pT Stage 731.610 <0.001 <0.001
T1 60.2% Reference
T2 51.1% 1.156(0.969-1.380)
T3 31.7% 1.835(1.584-2.126)
T4 17.9% 2.604(2.246-3.019)
Tx 4.2% 4.453(3.216-6.164)
pN Stage 620.680 <0.001 <0.001
N1 42.9% Reference
N2 32.2% 1.371(1.270-1.480)
N3a 19.7% 2.186(2.010-2.378)
N3b 9.2% 3.524(3.169-2.919)
No. of LNs 135.822 <0.001 <0.001
≤6 20.3% Reference
7-14 29.0% 0.586(0.536-0.640)
≥15 32.6% 0.390(0.356-0.427)

NI: not included in the multivariate survival analysis.

P values were adjusted for age, race, location, pathological grading, histotype stage, tumor stage and No. of LNs as covariates.