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. 2019 Nov 11;17:115. doi: 10.1186/s12951-019-0546-3

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — a Graphical representation of co-culture transwell model utilized to test the efficacy of LIP after BBB crossing on human glioblastoma U87 cells. b Cell viability assessed by MTT assay on U87 cells seeded in the basolateral compartment of the transwell system. Data are expressed as a mean ± SD of triplicates and analysed with unpaired one-tailed Student’s t test. ***p < 0.001