Table II.
Biomarker | High-grade tumors | Low-grade tumors | PIN |
---|---|---|---|
Podocalyxin | 54/55=0.98 (0.92–1.00) | 71/81=0.88 (0.80–0.92) | 62/77=0.81 (0.72–0.87) |
TRA-1-60 | 8/55=0.15 (0.08–0.24) | 17/80=0.21 (0.15–0.30) | 8/74=0.11 (0.06–0.18) |
TRA-1-81 | 7/54=0.13 (0.07–0.22) | 12/78=0.15 (0.10–0.23) | 6/75=0.08 (0.04–0.15) |
Only prostate tumor tissue slides were used to assess the sensitivity of the staining intensity for each protein. Point estimates of the sensitivity of the staining intensity with the 90% Wilson type confidence limits for each protein are shown in parentheses. PIN: Prostatic intraepithelial neoplasia.