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(a) Negative p53 immunostaining in poorly differentiated carcinoma of thyroid (Magnification - 20X, IHC). (b) Strong nuclear expression (arrow) of p53 in epithelial cells of anaplastic carcinoma. The interspersed lymphomonuclear infiltrate is negative for p53. (Magnification - 20X, IHC) (c) Stong nuclear expression of p53 in spindled and epithelial cells along with tumor giant cells (arrow) in anaplastic carcinoma (Magnification - 20X, IHC)
