Table 2.
Unadjusted proportional incidence ratios (PIR) by patient and tumor characteristics, Iowa, 1991–2015.
| HIV/AIDS Population | Iowa Population | PIR | 95% CI | ||
|---|---|---|---|---|---|
| (N=490) | (N=436,101) | ||||
| Cancer diagnosis | 1991–1998 | 160 | 130,168 | 1.09 | (0.96, 1.24) |
| year | 1999–2006 | 116 | 137,449 | 0.75 | (0.64, 0.88) |
| 2007–2015 | 214 | 168,484 | 1.13 | (1.02, 1.25) | |
| Cancer diagnosis | 00–29 | 39 | 10,837 | 3.20 | (2.37, 4.33) |
| age (years) | 30–39 | 118 | 13,619 | 7.71 | (6.59, 9.02) |
| 40–49 | 163 | 32,631 | 4.45 | (3.92, 5.04) | |
| 50–59 | 113 | 67,923 | 1.48 | (1.26, 1.74) | |
| 60–69 | 45 | 105,365 | 0.38 | (0.29, 0.50) | |
| 70+ | 12 | 205,726 | 0.05 | (0.03, 0.09) | |
| Race | White | 418 | 424,847 | 0.88 | (0.84, 0.91) |
| African American | 55 | 5,936 | 8.25 | (6.43, 10.58) | |
| Other | 17 | 5,318 | 2.85 | (1.78, 4.54) | |
| Sex | Female | 57 | 218,351 | 0.23 | (0.18, 0.30) |
| Male | 433 | 217,750 | 1.77 | (1.71, 1.83) | |
| Area of residence | Metro | 340 | 217,429 | 1.18 | (1.11, 1.25) |
| (71,979 missing) | Non-metro | 144 | 146,699 | 0.74 | (0.64, 0.85) |
| Insurance status | Insured | 117 | 152,539 | 0.63 | (0.56, 0.71) |
| (260,415 missing) | Medicaid | 67 | 6,367 | 8.65 | (7.09, 10.55) |
| Uninsured | 18 | 3,301 | 4.48 | (2.88, 6.97) | |
| Unknown | 12 | 13,693 | 0.72 | (0.42, 1.25) | |
| Site / Histology | Anus and Anal Canal / Squamous Cell Neoplasms | 45 | 896 | 44.70 | (33.84, 59.05) |
| Anus and Anal Canal / Other | 5 | 356 | 12.50 | (5.23, 29.90) | |
| Female Genital Organs / Squamous Cell Neoplasms | 13 | 7,104 | 1.63 | (0.95, 2.79) | |
| Kaposi Sarcoma | 90 | 324 | 247.22 | (205.13, 297.96) | |
| Liver and Intrahepatic Bile Duct / Adenocarcinomas | 13 | 3,418 | 3.39 | (1.98, 5.79) | |
| Lung and Bronchus / Adenocarcinomas | 19 | 19,444 | 0.87 | (0.56, 1.35) | |
| Lung and Bronchus / Squamous Cell Neoplasms | 8 | 12,710 | 0.56 | (0.28, 1.11) | |
| Lung and Bronchus / Other | 11 | 25,530 | 0.38 | (0.21, 0.69) | |
| Lymph Nodes / NHL, Burkitt lymphoma | 16 | 182 | 78.24 | (48.32, 126.69) | |
| Lymph Nodes / NHL, DLBCL | 76 | 6,549 | 10.33 | (8.40, 12.70) | |
| Lymph Nodes / NHL, T-cell | 10 | 639 | 13.93 | (7.54, 25.72) | |
| Lymph Nodes / NHL, Other | 41 | 9,675 | 3.77 | (2.81, 5.06) | |
| Lymph Nodes / Other | 24 | 2,554 | 8.36 | (5.66, 12.36) | |
| Male Genital Organs / Adenocarcinomas | 9 | 51,050 | 0.16 | (0.08, 0.30) | |
| Male Genital Organs / Squamous Cell Neoplasms | 8 | 531 | 13.41 | (6.74, 26.66) | |
| Male Genital Organs / Other | 7 | 6,867 | 0.91 | (0.44, 1.89) | |
| Oral Cavity and Pharynx / Squamous Cell Neoplasms | 6 | 6,930 | 0.77 | (0.35, 1.71) | |
| Skin / Nevi and Melanomas | 5 | 23,480 | 0.19 | (0.08, 0.45) | |
| Other Sites / Adenocarcinomas | 25 | 96,654 | 0.23 | (0.16, 0.34) | |
| Other Sites / Ductal and Lobular Neoplasms | 7 | 60,989 | 0.10 | (0.05, 0.21) | |
| Other Sites / Leukemias | 9 | 13,379 | 0.60 | (0.31, 1.14) | |
| Other Sites / Squamous Cell Neoplasms | 11 | 9,414 | 1.04 | (0.58, 1.87) | |
| Other Sites / Other | 32 | 77,426 | 0.37 | (0.26, 0.51) | |
| AIDS-defining vs | Kaposi Sarcoma | 90 | 324 | 247.22 | (205.13, 297.96) |
| Non-AIDS-defining | NHL, Burkitt lymphoma | 16 | 178 | 80.00 | (49.41, 129.54) |
| cancers | NHL, DLBCL | 76 | 6,292 | 10.75 | (8.74, 13.22) |
| (23 missing*) | NHL, T-cell | 10 | 635 | 14.02 | (7.59, 25.88) |
| NHL, Other | 41 | 9,572 | 3.81 | (2.84, 5.11) | |
| Primary central nervous system lymphoma | 0 | 368 | 0.00 | - | |
| Cervical | 0 | 3,002 | 0.00 | - | |
| Non-AIDS-defining cancers | 257 | 415,730 | 0.55 | (0.51, 0.60) |
*
23 cases are missing due to their cancers being diagnosed within 3 months of an HIV/AIDS diagnosis
Abbreviations: DLBCL: diffuse large B-cell lymphoma