shows images of a 32-year female with D1-2 Vertebral GCT (A,B – Plain Radiograph Cervicodorsal spine Lateral and Anteroposterior views; C,D – MRI Spine Coronal and Sagittal views showing D1-2 vertebral lesion with intrathoracic extension) managed with Denosumab and definitive RT (50.4Gy/28#), given in view of poor response to the former with evident response (E,F – Plain Radiograph Lateral and Anteroposterior views; G,H – MRI Spine Axial and Sagittal views post Denosumab and RT).