Fig. 2. (a) Comparison of formation and decay of compound I during the reaction of heme–Aβ(1–16) with m-CPBA, red, and heme–Aβ(1–40) with m-CPBA, blue. (b) Comparison of decay of compound I during the reaction of heme–Aβ(1–16) with m-CPBA, in the absence of the substrate, red; and in the presence of the substrate, green, and heme–Aβ(1–40) with m-CPBA, in the absence of the substrate, red; and in the presence of the substrate, green; in 50 mM PO43– buffer at pH 8. (c) Formation of compound I from heme–Aβ(1–16) in H2O, red, and in D2O, purple, in 50 mM PO43– buffer at pH/D 8. All kinetics were followed at 675 nm.
