Table 5.
Immune cell type abundance between the 11-IRG signature low-risk group and high-risk group in the total set.
| Abundance |
||||
|---|---|---|---|---|
| Immune cell type# | Low-risk (n = 121) | High-risk (n = 118) |
Method | P value |
| B cells naive | 0.006118* | 0.004982* | Mann Whitney test | 0.582 |
| B cells memory | 0 | 0 | Mann Whitney test | 0.018 |
| Plasma cells | 0.04045 | 0.03793 | Mann Whitney test | 0.662 |
| T cells CD8 | 0.1766 | 0.1224 | Mann Whitney test | 0.002 |
| T cells CD4 memory resting | 0.05931 | 0.08927 | Mann Whitney test | 0.315 |
| T cells CD4 memory activated | 0.02884 | 0.03178 | Mann Whitney test | 0.944 |
| T cells follicular helper | 0.05201 | 0.04484 | Mann Whitney test | 0.123 |
| T cells regulatory | 0.05578 | 0.03317 | Mann Whitney test | 0.0001 |
| T cells gamma delta | 0 | 0 | Mann Whitney test | 0.527 |
| NK cells resting | 0 | 0 | Mann Whitney test | 0.002 |
| NK cells activated | 0.04077 | 0.03975 | Mann Whitney test | 0.775 |
| Monocytes | 0.000449 | 0 | Mann Whitney test | 0.015 |
| Macrophages M0 | 0.08207 | 0.1324 | Mann Whitney test | 3.43e-05 |
| Macrophages M1 | 0.1044 | 0.09134 | Mann Whitney test | 0.144 |
| Macrophages M2 | 0.08075 | 0.07147 | Mann Whitney test | 0.635 |
| Dendritic cells resting | 0.02452 | 0.01757 | Mann Whitney test | 0.065 |
| Dendritic cells activated | 0.008952 | 0.01998 | Mann Whitney test | 0.073 |
| Mast cells resting | 0.03694 | 0.02397 | Mann Whitney test | 0.0001 |
| Mast cells activated | 0 | 0 | Mann Whitney test | 1.04e-05 |
| Eosinophils | 0 | 0 | Mann Whitney test | 0.123 |
| Neutrophils | 0 | 0 | Mann Whitney test | 0.055 |
*The data are presented as median. # The naive CD4 T cells were absent in all CC samples.