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. 2019 Oct 21;8(12):e1678921. doi: 10.1080/2162402X.2019.1678921

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© 2019 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — (a). Pre-treatment tissue biopsy; white boxes define two representative regions of interest (ROI) 1 and 2 enlarged in A1–E1 and A2–E2, respectively. (b). vascular panel; blue: DAPI, green: collagen IV, yellow: CD31, red: glycophorin A (GPA). (c). inflammatory panel; blue: DAPI, green: CD4, yellow: CD3, orange: CD8, teal: IBA1, magenta: CD68. (d). glia stem panel; blue: DAPI, green: nestin, purple: vimentin, yellow: proliferation cell nuclear antigen (PCNA). (e). glia differentiation panel; blue: DAPI, green: glial fibrillary acidic protein (GFAP), yellow: S100β, magenta: SOX2.