Figure 6.

Evaluation of apoptosis in CD4⁺ T cells in fungal sepsis. (a) The subpopulation of annexin-V-positive and PI-negative stained CD4⁺ T cells was considered to be undergoing early apoptosis, while the subpopulation of annexin-V-positive and PI-positive stained CD4⁺ T cells was considered to be undergoing late apoptosis. (b) The apoptosis rate of CD4⁺ T cells, as analyzed by ratio of annexin-V-positive and PI-positive/negative stained CD4⁺ T cells. (c) Relative RNA expression for the apoptotic gene BIM. Mean ± SD, six mice per group, ∗∗∗∗p < 0.0001.