Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic illustration of how the rs5743305 (TLR3 − 926T>A) variant increased the risk of breast cancer. TheTLR3 − 926A polymorphism leads to lower transcriptional activity than its wild type (−926T). Women carrying this SNP have lower expression of TLR3. Consequently, reduced activation of TLR3 may play a role in the increased risk of breast cancer.
