Vereschagin 1991.
Methods | Randomised: methods of randomisation and allocation concealment were not described. Double‐blind Placebo‐controlled Duration: 4 weeks |
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Participants | Number of participants: 60 participants were divided equally into 2 groups. Inclusion: patients with a mild form of multi‐infarct dementia, but the diagnosis criteria were not described. Baseline: the study groups had similar baseline compared parameters. |
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Interventions | Cere group: Cere 15 mL (10 mL in the morning and 5 mL in the evening) + 0.85% NaCl solution 200 mL Placebo group: placebo 15 mL (10 mL in the morning and 5 mL in the evening) + 0.85% NaCl solution 200 mL i.v. infusions twice daily for 28 days. |
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Outcomes | Clinical evaluations (by means of a special scale) EEG Psychological test of Arnold‐Kohlmann Response times |
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Notes | Only an abstract was found. Despite our efforts, detailed information could not be obtained. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Despite contacting study authors, detailed methods were not available. |
Allocation concealment (selection bias) | Unclear risk | Despite contacting study authors, detailed methods were not available. |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Despite contacting study authors, detailed methods were not available. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Despite contacting study authors, detailed methods were not available. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Despite contacting study authors, details were not available. |
Selective reporting (reporting bias) | Unclear risk | Despite contacting study authors, details were not available. |
Other bias | Unclear risk | Despite contacting study authors, details were not available. |