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. 2019 Nov 3;57(1):744–752. doi: 10.1080/13880209.2019.1666151

Table 4.

Pulmonary function was correlated with the expression of STAT4/STAT6 and MMP-9/TIMP-1.

Indicators FEV1 FVC FEV1/FVC% DLco%pred MMP-9/TIMP-1 STAT4/STAT6
FEV1   0.91 0.59 0.38 −0.55 −0.49
FVC 0.91*   0.23 0.21 −0.35 −0.3
FEV1/FVC% 0.59* 0.23*   0.48 −0.62 −0.55
DLco%pred 0.38* 0.21* 0.48*   −0.61 −0.51
MMP-9/TIMP-1 −0.55* −0.35* −0.62* −0.61*   0.71
STAT4/STAT6 −0.49* −0.30* −0.55* −0.51* 0.71*  

FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; DLco%pred: the predicted value of carbon monoxide diffusing capacity; STAT4: signal transducers and activators of transcription 4; STAT6: signal transducers and activators of transcription 6; MMP-9: matrix metalloproteinase-9; TIMP-1: tissue inhibitor of metalloproteinases-1.