Figure 6.

KFX activated IGF-1/Akt pathway in WIRS-induced ulcer rats. (A) The gastric samples were prepared with lysis buffer, resolved on 10% SDS-PAGE, and transferred to a PVDF membrane. Western blots were performed to detect the total or Akt, p-Akt, FoxO1, PTEN, IGF-1 using specific primary antibodies. (B) Densitometric analysis was used to quantify the levels of p-Akt/Akt, FoxO1, PTEN, IGF-1. The data were expressed as the means ± SD (n = 5). ^##p < 0.01, compared with the control group; *p < 0.05, **p < 0.01 compared with the model group. KFX: Kangfuxin liquid.