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The oxygen consumption rate of yeast cells treated with statins is low compared to the wild type strain. (a) Oxygen consumption of W303, W303 rho° and W303 cells treated with statins in YPD medium showed low oxygen consumption in cells treated with statins; (b) The respiration rate is higher when the same cultures were grown in YPD medium supplemented with ergosterol. The oxygen consumption rate is expressed as O2 nmol/ml, and the respiration rates was normalized for cell number.
