Figure 4. TCR clonality is associated with immune pathway dysregulation in breast tumors.

A. TCR clonality and richness for individual breast tumors with matched scRNA-seq and TCR-seq data. B. Heatmap of Morisita-Horn similarity index to quantify agreement of CDR3 clonotypes from duplicate TCR-seq data for the same breast tumor and between individual breast tumors. C. Hierarchical heatmap of EVA statistics of inter-cellular heterogeneity for immune pathways in each breast tumor T cell subtype.