Fig 6.

Gene set variation analyses (GSVA) of mucosal transcriptome from T cell reconstituted colitic mice using murine homologues of the human CSF-1 (A) and TNFα (B) induced gene sets. Data points representing individual mice are plotted in five quartile box plots (95% confidence interval) and demonstrate the increased expression of both gene sets in mouse colon and response to treatment. Naïve and isotype controls, n = 6. All remaining groups, n = 8. Veh = vehicle for JNJ527; Iso = isotype control for CNTO5048.