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. 2019 Nov 11;176(Suppl 1):S1–S20. doi: 10.1111/bph.14747
Nomenclature http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2552 http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2553
HGNC, UniProt https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:8157, http://www.uniprot.org/uniprot/Q99720 https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:28106, http://www.uniprot.org/uniprot/Q5BJF2
Agonists http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6684 [http://www.ncbi.nlm.nih.gov/pubmed/16463398?dopt=AbstractPlus] – Guinea pig
Selective agonists http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6678 [http://www.ncbi.nlm.nih.gov/pubmed/1658302?dopt=AbstractPlus], (http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6677
Antagonists http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6682 (pIC50 7.2) [http://www.ncbi.nlm.nih.gov/pubmed/10096443?dopt=AbstractPlus]
Selective antagonists http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6679 (pIC50 8.4) [http://www.ncbi.nlm.nih.gov/pubmed/7901723?dopt=AbstractPlus], http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6680 (pIC50 7.4) [http://www.ncbi.nlm.nih.gov/pubmed/8566098?dopt=AbstractPlus]
Labelled ligands [http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6683 (Agonist) [http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6685 (Agonist)
Comments The sigma2 receptor has been reported to be TMEM97 [http://www.ncbi.nlm.nih.gov/pubmed/28559337?dopt=AbstractPlus], a 4TM protein partner of NPC1, the Niemann‐Pick C1 protein, a 13TM cholesterol‐binding protein.